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Ferritin Heavy Chain 1 Primary Antibody Unconjugated Public Immunogen Range 65-100/183 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
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Mal-PEG2-VCP-Eribulin is an Eribulin-based drug-linker conjugate intended for antibody-drug conjugate (ADC) research. It comprises the Mal-PEG2-VCP linker covalently attached to Eribulin, a mechanistically unique microtubule inhibitor, and is supplied in small pack sizes for conjugation and preclinical studies.
Contains Mal-PEG2-VCP linker conjugated to Eribulin.
Mechanism: microtubule inhibitor for use as a cytotoxic payload.
Intended use: building block for antibody-drug conjugates and ADC research.
Key identifiers: CAS 2130869-18-8, formula C70H99N7O21, molecular weight ~1374.6.
Available in small pack sizes suitable for research (for example, 1 mg).
Typical reported purity: greater than 98%.
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An analog of valeric acid; inhibits class I HDACs (IC50s = ~2 mM); decreases the number of axon branches in sensory neurons isolated from newborn rat dorsal root ganglia; inhibits amyloid-β deposition and neuritic plaque formation and decreases escape latency in the Morris water maze test in the APP23 transgenic mouse model of Alzheimer's disease; has anticonvulsant activity in the pentylenetetrazole seizure threshold test in mice (ED50 = 0.71 mmol/kg); induces neurotoxicity at ≥1.2 mmol/kg
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Serum Amyloid A (SAA) is an acute-phase protein The concentration of SAA in blood increases rapidly when tissue damage or inflammation occurs It is considered as an early biomarker for the diagnosis of many inflammatory diseases SAA can also be used as an important indicator of infection
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